Auteur : Salloway, Stephen / Malloy, Paul F. / Duffy, James D.

Maison d'édition : American Psychiatric Publishing

Date de publication : 2001

Collation : x, 264 p. : ill.

ISBN : 08804800X

Langue : Anglais

Table des matières : 1. The frontal lobes and neuropsychiatric illness -- 2. The significance of frontal system disorders for medical practice and health policy -- 3. Frontal subcortical circuits : anatomy and function -- 4. The orbitofrontal cortex -- 5. Working memory dysfunction in schizophrenia -- 6. Lateralization of frontal lobe functions -- 7. Consciousness, self-awareness, and the frontal lobes -- 8. Regional prefrontal syndromes : a theoretical and clinical overview -- 9. Assessment of frontal lobe functions -- 10. Diagnosis and treatment of "Frontal Lobe" syndromes -- 11. Treatment strategies for patients with dysexecutive syndromes -- 12. Frontal lobe dysfuncton in secondary depression -- 13. The frontal lobes and schizophrenia -- 14. The frontal lobes and traumatic brain injury -- 15. The frontal lobes and content-specific delusions -- 16. Neurosurgical treatment for refractory obsessive-compulsive disorder : implications for understanding frontal lobe function

Résumé : This exciting volume brings together the latest work of 26 recognized experts in clinical neuropsychiatry, neuropsychology, neuroscience, and neuroimaging. Its chapters are organized into sections that cover a broad range of topics related to advances in our understanding of normal and abnormal frontal lobe functions.

• Part 1 introduces frontal lobe dysfunction as a common pathway leading to social and occupational disability, arguing that our aging population with its decline in executive cognitive abilities mandates corresponding eligibility and treatment changes in public and private health disability policies.
• Part 2 delineates the anatomy and neurochemistry of the extended frontal systems underlying neuropsychiatric illness, including colorful illustrations of three key prefrontal-subcortical circuits; a description of the functional anatomy of the orbitofrontal cortex and its relationship to obsessive-compulsive disorder (OCD); the intricate pharmacology of working memory systems and how they apply to schizophrenia; the lateralization of prefrontal cognitive functions; and a framework for understanding the role played by the prefrontal cortex in consciousness and self-awareness.
• Part 3 clarifies the overused diagnosis “frontal lobe syndrome” seen in clinical practice, identifying three prefrontal syndromes for further study—dorsolateral dysexecutive syndrome, orbitofrontal disinhibited syndrome, and mesial frontal apathetic syndrome—that align with the anatomical systems described in Part 2 of this volume. Also included are common problems—and suggested solutions—in diagnosis and treatment, a practical overview of the assessment of frontal lobe functions with guidelines for bedside and formal neuropsychological examination, and comprehensive treatment strategies.
• Part 4 covers the role of the frontal lobes in major neuropsychiatric illnesses, discussing evidence that shows prefrontal and anterior temporal hypometabolism in primary and secondary depression; reviewing anatomical, imaging, and neurochemical studies in schizophrenia; describing the neuropsychological and neuropsychiatric sequelae of closed head injury; summarizing the neurological substrates related to interesting and often dramatic cases of content-specific delusions; and concluding with a report on the stereotactic neurosurgical treatment of refractory OCD and its implications for understanding frontal lobe function.

Mots-clés : Troubles mentaux organiques / Lobes frontaux - Physiopathologie / Cerveau - Maladies - Physiopathologie

Cote : WL 307 F934 2001