Auteur : Hof, Patrick R. / Giannakopoulos, P. (Panteleimon)

Maison d'édition : Karger

Date de publication : 2009

Collation : x, 184 p. : ill.

Collection : Frontiers of neurology and neuroscience ; v. 24

ISBN : 9783805590150

Langue : Anglais

Table des matières : 1. Clinical investigations in primary care -- 2. The concept of mild cognitive impairment : relevance and limits in clinical practice -- 3. Pathological substrates of cognitive decline in Alzheimer's disease - 4. Functional imaging in mild cognitive impairment and early Alzheimer's disease : is it pertinent? -- 5. Electrophysiological markers of rapid cognitive decline in mild cognitive impairment -- 6. The future : new methods of imaging exploration in Alzheimer's disease -- 7. Pharmacological interventions in primary care : hopes and illusions -- 8. Investigations in primary care -- 9. The concept of vascular cognitive impairment -- 10. Defining the neuropathological background of vascular and mixed dementia and comparison with magnetic resonance imaging findings -- 11. Is it possible to treat vascular dementia? -- 12. Dementia with lewy bodies : clinical diagnosis and therapeutic approach -- 13. Significance of brain lesions in Parkinson disease dementia and Lewy body dementia -- 14. Delineating dementia with Lewy bodies : can magnetic resonance imaging -- 15. Pharmacotherapy of Parkinson disease dementia and Lewy body dementia -- 16. Clinical features and diagnosis of frontotemporal dementia -- 17. Neuropathological spectrum of frontal lobe dementias -- 18. Frontemporal dementia neuroimagning : a guide for clinicians -- 19. Frontotemporal dementia : therapeutic interventions

Résumé : This publication summarizes the most recent advances in neurobiology, diagnostic approaches and therapeutics of the major dementing illnesses such as Alzheimer's disease, frontotemporal dementia, Lewy body disease, and vascular dementia. In a succinct, practical and comprehensive manner, it provides an updated view of the disorders likely to be encountered in a daily practice. Each section is focused on a major form of dementia and is organized following the same scheme reviewing the pathophysiology of the disease, its diagnostic challenges, its characteristic neuroimaging features, therapeutic interventions and patient management issues. Avoiding an overspecialized approach, the book bridges the gap between clinical practice, advanced imaging, recent therapeutics and basic sciences. Thus, it serves as an excellent guide for mental health professionals working in the field of dementia as well as primary care physicians and students.

Mots-clés : Démence / Démence - Diagnostic / Démence - Traitement / Imagerie pour le diagnostic - Méthodologie

Cote : WM 220 H697d 2009