Auteur : Genazzani, Andrea R.

Maison d'édition : Taylor and Francis

Date de publication : 2006

Collation : xv, 312 p. : ill.

Collection : Controversial Issues in Climacteric Medicine Series

ISBN : 9781842143117

Langue : Anglais

Table des matières : 1. Magnitude and impact of osteoporosis and fractures -- 2. Impact of osteoporosis on quality of life and quality of life on osteoporosis : rationale and methodology for accurate assessment -- 3. Novel signals determining skeletal cell fate and function -- 4. Sex steroid hormones and bone formation -- 5. The effect of sex steroids on osteoclast function -- 6. Calcium and vitamin D : regulation of mineral homeostasis -- 7. Genetic regulation of bone mass -- 8. Bone mineral acquisition during infancy and adolescence -- 9. Osteoporosis : influence of life-style -- 10. Postmenopausal osteoporosis and dental health -- 11. Bone quality -- 12. Diagnosis : clinical, hormonal and biochemical evaluation -- 13. Advanced imaging assessment of bone quality -- 14. Quantitative ultrasonometry of bone in the management of postmenopausal women -- 15. Awareness of osteoporosis and related treatments -- 16. Intervention thresholds for osteoporosis -- 17. Vitamin D and calcium supplements -- 18. Estrogen dose response in bone density and bone histology -- 19. Effects of oral contraceptive preparation on bone health -- 20. Hormone replacement threrapy -- 21. New physiologic approach to prevention of postmenopausal osteoporosis -- 22. Selective estrogen receptor modulators -- 23. Bisphosphonates in the management of osteoporosis -- 24. Phytoestrogens : food or drug? -- 25. Tibolone -- 26. Understanding the role of aromatizable androgens in bone-sparing -- 27. Strontium ranelate : a new first-line treatment for patients with postmenopausal osteoporosis -- 28. Reconciling risks and benefits of hormone replacement therapy in a single outcome : the QALY approach -- 29. Prevent, treat and maintain : how to optimize the management of postmenopausal osteoporosis -- 30. Transdermal hormone therapy : effects on bone -- 31. Progestogens and bone -- 32. Effect of different dose options of continuous combined hormone therapy on bone and bone marker N-terminal propeptide of type I procollagen : results from a long-term study in Finnish postmenopausal women -- 33. The use of alendronate in osteoporosis treatment : 10-year experience

Résumé : The book is the first major review of menopause-associated osteoporosis, post WHI. The book has in-depth sections on the pathogenesis, epidemiology, and diagnosis of osteoporosis. The chief focus is on medical prevention and treatment, and includes chapters on hormone replacement therapy, bisphosphonates, selective estrogen receptor modulators (SERMs), vitamin D derivatives, calcium supplements, androgens, and tibolone.

Mots-clés : Ostéoporose / Ménopause / Ostéoporose - Prévention / Ostéoporose - Traitement

Cote : WE 250 P858 2006