Auteur : Moldin, Steven O. / Rubenstein, John L.R. 1955-

Maison d'édition : Taylor and Francis;CRC Press

Date de publication : 2006

Collation : 526 p. : ill.

ISBN : 0849327326

Langue : Anglais

Table des matières : 1. Autism spectrum disorders : phenotype and diagnosis -- 2. Past and future perspectives on autism epidemiology -- 3. Genetic basis of autism -- 4. Finding genes in spite of heterogeneity : endophenotypes, QTL mapping, and expression profiling in autism -- 5. A mixed epigenetic and genetic and mixed De Novo and inherited model for autism -- 6. Neurobiology of related disorders : Fragile X Syndrome -- 7. Fear and anxiety pathways -- 8. Cerebellar networks and autism : an anatomical hypothesis -- 9. Language in autism -- 10. Prefrontal cortex -- 11. The social brain, amygdala, and autism -- 12. The thalamus and neuromodulatory systems -- 13. Modeling features of autism in animals -- 14. Neuroanatomical and neurochemical studies of the autistic brain : current thought and future directions -- 15. The social brain in autism : perspectives from neuropsychology and neuroimaging -- 16. Structural neuroimaging -- 17. Neeuropsychology and neurophysiology of autism spectrum disorders -- 18. Pharmacological treatments -- 19. Behavioral, educational, and developmental treatments for autism -- 20. The costs of autism

Résumé : Taking an all-inclusive look at the subject, Understanding Autism: From Basic Neuroscience to Treatment reviews state-of-the-art research on the diagnosis, treatment, and prevention of autism. The book addresses potential mechanisms that may underlie the development of autism and the neural systems that are likely to be affected by these molecular, genetic, and infectious etiologies. It reviews key findings that inform diagnosis, epidemiology, clinical neuroscience, and treatment.

The book concludes with a discussion of the economic cost of autism and provides a biomedical and public health perspective of the impact of this devastating disease. With chapters authored by clinical and basic researchers at the forefront of molecular and systems neuroscience, clinical neuroscience, and health economics, the book presents a powerful and comprehensive synthesis of current research on autism and its underlying neural substrates. The book's two editors are considered elite pioneers in this area of research. Dr. Rubenstein was recently elected to the highly prestigious Institute of the Medicine, an honor reserved for those most committed to professional achievement and public service.

Mots-clés : Autisme / Autistes / Autisme - Aspect psychologique / Autisme - Génétique

Cote : WM 203.5 M717u 2006