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Managing treatment-resistant depression : road to novel therapeutics

Favoris Imprimer
Livre électronique

Quevedo, João (Éditeur intellectuel) / Riva-Posse, Patricio (Éditeur intellectuel) / Bobo, William V. (Éditeur intellectuel)

Academic Press

2022

1 ressource en ligne

Format PDF

9780128240687

Anglais

1. Defining treatment-resistant depression, difficult-to-treat depression, and staging treatment intensity -- 2. Clinical and epidemiological predictors of treatment-resistant depression -- 3. The economic burden of treatment-resistant depression: Cost-of-illness perspective -- 4. The neurobiology of treatment-resistant depression -- 5. Modeling treatment-resistant depression in the preclinical setting -- 6. Treatment algorithms for treatment-resistant depression -- 7. Tools to aid precision treatments to prevent or manage treatment-resistant depression (TRD): Pharmacogenomics, machine learning, and artificial intelligence -- 8. Tricyclic antidepressants for treatment-resistant depression -- 9. Monoamine oxidase inhibitors for treatment-resistant depression -- 10. Switching antidepressants in patients with treatment-resistant depression -- 11. Adjunctive strategies for treatment-resistant depression -- 12. Combining antidepressants to address treatment-resistant depression -- 13. Ketamine/esketamine for treatment-resistant depression -- 14. Psychedelic agents for treatment-resistant depression -- 15. Inflammation and treatment resistance: Mechanisms and treatment implications -- 16. Opioid agents for treatment-resistant depression -- 17. Transcranial magnetic stimulation for treatment-resistant depression -- 18. tDCS for treatment-resistant depression -- 19. ECT for treatment-resistant depression -- 20. MST for treatment-resistant depression -- 21. VNS for treatment-resistant depression -- 22. Deep brain stimulation for treatment-resistant depression -- 23. Other neurosurgical interventions for treatment-resistant depression -- 24. Treatment-resistant psychotic depression -- 25. Evidence-based psychotherapy for treatment-resistant depression -- 26. Treatment-resistant bipolar depression -- 27. Treatment-resistant depression in children and adolescents -- 28. Treatment-resistant depression in geriatrics -- 29. Identification and management of anxious depression in patients with treatment-resistant depression -- 30. Managing treatment-resistant depression with comorbid personality disorders -- 31. Managing treatment-resistant depression with comorbid substance use disorders -- 32. Managing treatment-resistant depression in the setting of chronic pain -- 33. Inhaled gases for treatment-resistant major depression -- 34. Drugs under investigation for treatment-resistant depression -- 35. Chronotherapeutics for treatment-resistant depression -- 36. Managing treatment resistant depression in primary care settings -- 37. Treatment-resistant depression in pregnancy, the postpartum period, and transition to menopause -- 38. Lifestyle interventions for treatment-resistant depression -- 39. Managing the risk of suicide in people with treatment-resistant depression -- 40. Maintaining motivation and preserving the therapeutic alliance as tools to overcome treatment-resistant depression

Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD.

Dépression / Dépression - Traitement / Antidépresseurs / Psychothérapie

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