Auteur : Cicchetti, Dante / Walker, Elaine F.

Maison d'édition : Cambridge University Press

Date de publication : 2003

Collation : xii, 558 p. : ill.

ISBN : 0521802253

Langue : Anglais

Table des matières : Part one : Basic mechanisms in prenatal, perinatal, and postnatal neurodevelopmental processes and their associations with high-risk conditions and adult mental disorders
1. Principles of neurobehavioral teratology -- 2. The neuro developmental consequences of very preterm birth : brain plasticity and its limits -- 3. Neurodevelopment during adolescence -- 4. Prenatal risk factors for schizophrenia -- 5. Obstetric complications and neurodevelopmental mechanisms in schizophrenia -- 6. Maternal influences on prenatal neural development contributing to schizophrenia
Part two : Animal models of neurodevelopment and psychopathology
7. On the relevance of prenatal stress to developmental psychopathology : a primate model -- 8. Nonhuman primate models of developmental psychopathology : problems and prospects -- 9. Early orbitofrontal-limbic dysfunction and autism
Part three : Models of the nature of genetic and environmental influences on the developmental course of psychopathology
10. Genetic structure of neurodevelopmental traits : implications for the development (and definition of) psychopathology -- 11. Prospects and problems in the search for genetic influences on neurodevelopment and psychopathology : apllication to childhood disruptive disorders -- 12. Developmental psychoneuroimmunology : the role of crytokine network activation in the epigenesis of developmental psychopathology -- 13. The Hypothalamic-Pituitary-Adrenal System (HPA) and the development of agressive, antisocial, and substance abuse disorders -- 14. Neuroendocrine functioning in maltreated children -- 15. Toward unraveling the premorbid neurodevelopmental risk for schizophrenia -- 16. Interactions of the dopamine, serotonin, and GABA systems during childhod and adolescence : influence of stress on the vulnerability for psychopathology
Part four : The neurodevelopmental course of illustrative high-risk conditions and mental disorders
17. Neurobiology of personality disorders : implications for a neurodevelopmental model -- 18. Genesis and epigenesis of psychopathology in children with depressed mothers : toward an integrative biopsychosocial perspective -- 19. The neurobiology of child and adolescent depression : current knowledge and future directions -- 20. Psychosocial stressors as predisposing factors to affective illness and PTSD : potential neurobiological mechanisms and theoretical implications -- 21. Neurohormonal aspects of the development of psychotic disorders

Résumé : This volume presents a burgeoning perspective on the origins of psychopathology , one that focuses on the development of the human central nervous systems. The contemporary neurodevelopmental perspective assumes that mental dosorders result from etiologic factors that alter the normal course of brain development. Defined here in its broadest sense, neurodevelopmetn is process that begins at conception and extends throughout the lifespan. We now know that it is a complex process and that its course can be altered by a host of factors, ranging from inherited genetic liabilities to psychosocial stressors.
This book features the very best, cutting-edge thinking in the coverging fields of developmental window represented is broad, extending from the rpenatal period through adulthood, and the authors cover a broad range of etiologic factors and a spectrum of clinical disorders. Moreover, the contributors do not hesitate to use the opportunity to hypothesize about underlying mechanisms and to speculate on future research directions.

Mots-clés : Maladies mentales - Étiologie / Schizophrénie - Physiopathologie / Schizophrénie - Étiologie / Neurologie du développement / Psychopathologie

Cote : WM 140 C568n 2003